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January 31, 2003
MEDICURE CELEBRATES SUCCESSFUL PHASE II RESULTS
WITH THE WINNIPEG INVESTMENT COMMUNITY

WINNIPEG, Manitoba - (January 31, 2003) - Medicure Inc. (TSX: MPH), a cardiovascular biotechnology company, was pleased to host a special gathering for members of the Winnipeg investment community yesterday to celebrate the positive results from the MEND-1 Phase II trial.

With the promising results from the recently completed MEND-1 Phase II trial, Dr. Friesen added that, "we are very keen to move quickly toward proceeding with additional Phase II trials and then on to Phase III. In fact, at a meeting with the FDA, they strongly supported us carrying on a Phase II/III. So we're very encouraged to proceed aggressively, not only to the bypass, but also to acute MI or acute heart attack studies, and stroke trial and we are well positioned financially to continue on the current Phase II track."

Commenting on suggestions and inferences that Medicure is actively seeking new financing options, Chairman, President and CEO, Albert D. Friesen, Ph.D., stated emphatically: "This is absolutely not correct. As at November 30, 2002, the end of our second quarter, the Company reported a solid cash position and cash equivalents totaling approximately $5.7 million. As such, we have sufficient capital to undertake a further Phase II study that we've planned all along - the bypass and stroke Phase II study."

In addition, Dr. Friesen stated that the interest level from potential partners has increased since the Company announced the positive results from the MEND-1 trial. "We are in discussions with several large pharmaceutical companies regarding potential partnership opportunities for our Phase III trial and we hope to make an announcement on this later this year," he said.

About Medicure Inc.
Medicure Inc. is a cardiovascular drug discovery and development Company focused on developing effective therapeutics for unmet needs in the field of cardiovascular medicine including the prevention and treatment of ischemia, ischemic reperfusion injury, and stroke.

This press release contains forward-looking statements that involve risks, which may cause actual results to differ materially from the statements made, and accordingly may be deemed to be forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements are made as of the date hereof, and the Company disclaims any intention and has no obligation or responsibility to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

For additional information contact:

Derek Reimer
Chief Financial Officer
Medicure Inc.
Tel. 204-487-7412
Fax 204-488-9823
info@medicure.com

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