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June 13, 2003
Medicure Announces Private Placement for Approximately $7.0 Million

WINNIPEG, Manitoba - (June 13, 2003). In response to institutional interest, Medicure Inc. (TSX:MPH), a cardiovascular drug discovery and development company, is pleased to announce that it has entered into an Agency agreement with a syndicate led by Research Capital Corporation, and including First Associates Investments Inc. and Paradigm Capital Inc. (the "Agents"), for the issuance and sale of 8,200,000 common shares at a price of $0.85 per share representing gross proceeds of approximately $7,000,000. The Agents have also been granted an over-allotment option, exercisable at any time until 30 days following the Closing, to increase the size of the Offering up to a total of approximately 9,000,000 shares, on the same terms and conditions as the initial Offering. Total gross proceeds including the exercise of the over-allotment option would be $7,650,000. It is expected that the deal will close on or about June 26, 2003, subject to regulatory approval.

"In January of this year, Medicure announced positive results from our Phase II study to establish the efficacy and safety of Medicure's lead compound, MC-1, as a cardioprotective treatment to reduce heart damage associated with acute ischemic and reperfusion injury," said Albert D. Friesen, Ph.D, Medicure's President and Chief Executive Officer.

"This financing will enable us to build on our recent successes, accelerating the timetable for advancing this and other clinical development programs towards the market," he stated.

"We are very pleased to have some of the most knowledgeable and sophisticated biotech investors participating in this private placement financing. We feel that this commitment from these institutional investors represents a strong endorsement of both our lead product, MC-1, and our latest drug candidate, MC-4232 and our upcoming clinical activities," added Dr. Friesen.

About Medicure Inc.
Medicure Inc. is a cardiovascular drug discovery and development Company focused on developing effective therapeutics for unmet needs in the field of cardiovascular medicine. The lead drug, MC-1, is focused on the prevention and treatment of ischemia, ischemic reperfusion injury, and stroke. The cardiovascular and stroke markets are the largest pharmaceutical markets with annual global sales of over US $70 billion. In the United States alone, more than 7 million patients suffer some form of Acute Myocardial Infarction (heart attack) annually, 6.2 million suffer from angina and 3.0 million undergo bypass surgery or angioplasty procedure.

MC-1, has shown strong potential for treating various forms of cardiovascular diseases and stroke The traditional classes of cardiovascular drugs, such as beta-blockers, ACE inhibitors, and calcium channel blockers have not filled the gap in effectiveness required to stem the increase in cardiovascular disease. MC-1 has demonstrated the ability to become a key therapeutic agent in the fight against cardiovascular diseases and stroke as a new class of drug. Additionally, the naturally occurring lead drug is used as a scaffold to developing a new class of therapeutics, which focus on cardioprotection against ischemic reperfusion injury and stroke.

This press release contains forward-looking statements that involve risks, which may cause actual results to differ materially from the statements made, and accordingly may be deemed to be forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements are made as of the date hereof, and the Company disclaims any intention and has no obligation or responsibility to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

For more information, please contact:

Derek Reimer
Chief Financial Officer

Don Bain
Director of Investor & Public Relations

Medicure Inc.
888-435-2220
204-488-9823 fax
info@medicure.com

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