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April 6, 2004
Medicure To Host Conference Call On MC-4232 Program

WINNIPEG, Manitoba - (April 6, 2004) - Medicure Inc. (TSX: MPH/Amex: MCU), a cardiovascular drug discovery and development company will host a Conference Call on Wednesday, April 7, 2004, to discuss its Phase II trial as part of its development program for MC-4232.

A News Release regarding the Phase II trial and the development program will be issued prior to the opening of the markets on April 7, 2004, with the Conference Call taking place at 11 a.m. Eastern Daylight Time.

SUMMARY
Title of Conference: Medicure Hypertension Trial Update

Date of Conference Call: Wednesday, April 7, 2004

Time of Call: 11 a.m. Eastern Daylight Time

Dial-in Numbers for 1-877-461-2814 (Toll Free)
Participants 416-695-9753 (Toronto area participants)

Confirmation # for Call: T490260M

About Medicure Inc.
Medicure Inc. is a cardiovascular drug discovery and development Company focused on developing effective therapeutics for unmet needs in the field of cardiovascular medicine. The Company's lead drug, MC-1, is focused on the prevention and treatment of ischemia, ischemic reperfusion injury, and stroke. The cardiovascular and stroke market is the largest pharmaceutical sector with annual global sales of over US $70 billion.

The Company's second product candidate, MC-4232, is being targeted for the treatment of hypertension, a common disorder in which blood pressure remains abnormally high. Approximately 73% of the more than 50 million adult Americans who have hypertension, are not adequately treated.

Medicure also has a medicinal chemistry based Drug Discovery program focused on discovery and advancement of novel small molecule, anti-ischemics and anti-thrombotics towards human clinical studies.

This news release contains forward-looking statements that involve risks, which may cause actual results to differ materially from the statements made, and accordingly may be deemed to be forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements are made as of the date hereof, and the Company disclaims any intention and has no obligation or responsibility to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

For more information, please contact:

Derek Reimer
Chief Financial Officer

Don Bain
Director of Investor & Public Relations

Medicure Inc.
888-435-2220
204-488-9823 fax
info@medicure.com

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